Anti-GSR antibody (273-522) (STJ113969)

Name: Anti-GSR antibody (273-522) (STJ113969)
SKU: STJ113969
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ113969

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Short Description	Rabbit polyclonal GSR (273-522) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/ELISA
Host	Rabbit
Reactivity	Human/Mouse
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:500-1:2000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	GSR
Gene ID	2936
Uniprot ID	GSHR_HUMAN
Immunogen Region	273-522
Immunogen Sequence	MISTNCTEELENAGVEVLKF SQVKEVKKTLSGLEVSMVTA VPGRLPVMTMIPDVDCLLWA IGRVPNTKDLSLNKLGIQTD DKGHIIVDEFQNTNVKGIYA VGDVCGKALLTPVAIAAGRK LAHRLFEYKEDSKLDYNNIP TVVFSHPPIGTVGLTEDEAI HKYGIENVKTYSTSFTPMYH AVTKRKTKCVMKMVCANKEE KVVGIHMQGLGCDEMLQGFA VAVKMGATKADFDNTVAIH
Specificity	Recombinant fusion protein containing a sequence corresponding to amino acids 273-522 of human GSR (NP_000628.2).

Function	Catalyzes the reduction of glutathione disulfide (GSSG) to reduced glutathione (GSH). Constitutes the major mechanism to maintain a high GSH:GSSG ratio in the cytosol.
Protein Name	Glutathione Reductase - Mitochondrial Gr Grase
Database Links	Reactome: R-HSA-2408550 P00390-2 Reactome: R-HSA-3299685 Reactome: R-HSA-499943 P00390-2 Reactome: R-HSA-5628897 P00390-2 Reactome: R-HSA-9818027 P00390-2
Cellular Localisation	Isoform Mitochondrial: Mitochondrion Isoform Cytoplasmic: Cytoplasm
Alternative Antibody Names	Anti-Glutathione Reductase - Mitochondrial antibody Anti-Gr antibody Anti-Grase antibody Anti-GSR antibody Anti-GLUR antibody Anti-GRD1 antibody

Information sourced from Uniprot.org