| Host: |
Rabbit |
| Applications: |
WB/IF |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-GRPEL1 (1-217) is suitable for use in Western Blot and Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:200-1:2000IF/ICC 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
GRPEL1 |
| Gene ID: |
80273 |
| Uniprot ID: |
GRPE1_HUMAN |
| Immunogen Region: |
1-217 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-217 of human GRPEL1 (NP_079472.1). |
| Immunogen Sequence: |
MAAQCVRLARRSLPALALSL RPSPRLLCTATKQKNSGQNL EEDMGQSEQKADPPATEKTL LEEKVKLEEQLKETVEKYKR ALADTENLRQRSQKLVEEAK LYGIQAFCKDLLEVADVLEK ATQCVPKEEIKDDNPHLKNL YEGLVMTEVQIQKVFTKHGL LKLNPVGAKFDPYEHEALFH TPVEGKEPGTVALVSKVGYK LHGRTLRPALVGVVKEA |
| Function | Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins. |
| Protein Name | Grpe Protein Homolog 1 - MitochondrialHmgeMt-Grpe#1 |
| Database Links | Reactome: R-HSA-1268020 |
| Cellular Localisation | Mitochondrion Matrix |
| Alternative Antibody Names | Anti-Grpe Protein Homolog 1 - Mitochondrial antibodyAnti-Hmge antibodyAnti-Mt-Grpe#1 antibodyAnti-GRPEL1 antibodyAnti-GREPEL1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
