• Western blot analysis of extracts of various cell lines, using GRM1 antibody (STJ113802) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.

Anti-GRM1 antibody (920-1140) (STJ113802)

SKU:
STJ113802

Shipping:
Free Shipping
Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-GRM1 (920-1140) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: GRM1
Gene ID: 2911
Uniprot ID: GRM1_HUMAN
Immunogen Region: 920-1140
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 920-1140 of human GRM1 (NP_001264993.1).
Immunogen Sequence: NETACNQTAVIKPLTKSYQG SGKSLTFSDTSTKTLYNVEE EEDAQPIRFSPPGSPSMVVH RRVPSAATTPPLPSHLTAEE TPLFLAEPALPKGLPPPLQQ QQQPPPQQKSLMDQLQGVVS NFSTAIPDFHAVLAGPGGPG NGLRSLYPPPPPPQHLQMLP LQLSTFGEELVSPPADDDDD SERFKLLQEYVYEHEREGNT EEDELEEEEEDLQAASKLTP D
Tissue Specificity Detected in brain.
Function G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol-calcium second messenger system. May participate in the central action of glutamate in the CNS, such as long-term potentiation in the hippocampus and long-term depression in the cerebellum. May function in the light response in the retina.
Protein Name Metabotropic Glutamate Receptor 1
Mglur1
Database Links Reactome: R-HSA-416476
Reactome: R-HSA-420499
Reactome: R-HSA-6794361
Reactome: R-HSA-9717207
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Metabotropic Glutamate Receptor 1 antibody
Anti-Mglur1 antibody
Anti-GRM1 antibody
Anti-GPRC1A antibody
Anti-MGLUR1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance