Anti-GRK7 antibody (371-420 aa) (STJ93437)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human GRK7 at the amino acid range 371-420
General Information
| Short Description | Rabbit polyclonal anti-Rhodopsin kinase GRK7 (371-420 aa) for use in WB, IF and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IF 1:200-1:1000ELISA 1:20000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GRK7 |
| Gene ID | 131890 |
| Uniprot ID | GRK7_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human GRK7 at the amino acid range 371-420 |
| Immunogen Region | 371-420 aa |
| Specificity | GRK 7 Polyclonal Antibody detects endogenous levels of GRK 7 protein. |
Additional Info
| Post Translational Modifications | Autophosphorylated in vitro at Ser-490. Phosphorylation at Ser-36 is regulated by light and activated by cAMP. |
| Function | Retina-specific kinase involved in the shutoff of the photoresponse and adaptation to changing light conditions via cone opsin phosphorylation, including rhodopsin (RHO). |
| Protein Name | Rhodopsin Kinase Grk7G Protein-Coupled Receptor Kinase 7G Protein-Coupled Receptor Kinase Grk7 |
| Database Links | Reactome: R-HSA-2514859 |
| Cellular Localisation | MembraneLipid-Anchor |
| Alternative Antibody Names | Anti-Rhodopsin Kinase Grk7 antibodyAnti-G Protein-Coupled Receptor Kinase 7 antibodyAnti-G Protein-Coupled Receptor Kinase Grk7 antibodyAnti-GRK7 antibodyAnti-GPRK7 antibody |
Information sourced from Uniprot.org