• Western blot with Anti-GRK6 Antibody (STJ501286) on HeLa cell extract at 1:500 dilution in buffer.

Anti-GRK6 antibody (500-550) (STJ501286)

SKU:
STJ501286-100

€551.88
Shipping:
Free Shipping
Current Stock:
Host: Rabbit
Applications: ELISA/IHC/IP/WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-GRK6 (500-550) is suitable for use in ELISA, Immunohistochemistry, Immunoprecipitation and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Purification: Affinity Purified
Concentration: 0.5-1.5 µg/µl
Dilution Range: WB: 1:2, 500-1:5, 000
ELISA: 1:50, 000
IP: 1:200
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: GRK6
Gene ID: 2870
Uniprot ID: GRK6_HUMAN
Immunogen Region: 500-550
Immunogen: Synthetic peptide taken within amino acid region 500-550 on human G protein-coupled receptor kinase 6 protein.
Tissue Specificity Widely expressed.
Post Translational Modifications It is uncertain whether palmitoylation is on Cys-561 and/or Cys-562 and/or Cys-565.
Function Specifically phosphorylates the activated forms of G protein-coupled receptors. Such receptor phosphorylation initiates beta-arrestin-mediated receptor desensitization, internalization, and signaling events leading to their desensitization. Seems to be involved in the desensitization of D2-like dopamine receptors in striatum and chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis. Phosphorylates rhodopsin (RHO) (in vitro) and a non G-protein-coupled receptor: LRP6 during Wnt signaling (in vitro).
Protein Name G Protein-Coupled Receptor Kinase 6
G Protein-Coupled Receptor Kinase Grk6
Database Links Reactome: R-HSA-418555
Cellular Localisation Membrane
Lipid-Anchor
Alternative Antibody Names Anti-G Protein-Coupled Receptor Kinase 6 antibody
Anti-G Protein-Coupled Receptor Kinase Grk6 antibody
Anti-GRK6 antibody
Anti-GPRK6 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance