Anti-GRK3 antibody (589-688) [S2MR] (STJ11103652)

Name: Anti-GRK3 antibody (589-688) [S2MR] (STJ11103652)
SKU: STJ11103652
Availability: InStock

⇓ Datasheet ⇓ SDS Citations

SPECIFICATIONS

ClonalityMonoclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ11103652

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Short Description	Rabbit monoclonal GRK3 (589-688) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/ELISA
Host	Rabbit
Reactivity	Human
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Monoclonal
Clone ID	S2MR
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:500-1:1000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	GRK3
Gene ID	157
Uniprot ID	ARBK2_HUMAN
Immunogen Region	589-688
Immunogen Sequence	EWRGEGESRQNLLTMEQILS VEETQIKDKKCILFRIKGGK QFVLQCESDPEFVQWKKELN ETFKEAQRLLRRAPKFLNKP RSGTVELPKPSLCHRNSNGL
Specificity	A synthetic peptide corresponding to a sequence within amino acids 589-688 of human GRK3 (P35626).

Post Translational Modifications	Ubiquitinated.
Function	Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors.
Protein Name	G Protein-Coupled Receptor Kinase 3 Beta-Adrenergic Receptor Kinase 2 Beta-Ark-2
Database Links	Reactome: R-HSA-418555 Reactome: R-HSA-8856825
Cellular Localisation	Postsynapse Presynapse
Alternative Antibody Names	Anti-G Protein-Coupled Receptor Kinase 3 antibody Anti-Beta-Adrenergic Receptor Kinase 2 antibody Anti-Beta-Ark-2 antibody Anti-GRK3 antibody Anti-ADRBK2 antibody Anti-BARK2 antibody

Information sourced from Uniprot.org