| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | GRK3 |
| Gene ID: | 157 |
| Uniprot ID: | ARBK2_HUMAN |
| Immunogen Region: | 1-300 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human ADRBK2 (NP_005151.2). |
| Immunogen Sequence: | MADLEAVLADVSYLMAMEKS KATPAARASKRIVLPEPSIR SVMQKYLAERNEITFDKIFN QKIGFLLFKDFCLNEINEAV PQVKFYEEIKEYEKLDNEED RLCRSRQIYDAYIMKELLSC SHPFSKQAVEHVQSHLSKKQ VTSTLFQPYIEEICESLRGD IFQKFMESDKFTRFCQWKNV ELNIHLTMNEFSVHRIIGRG GFGEVYGCRKADTGKMYAMK CLDKKRIKMKQGETLALNE |
| Post Translational Modifications | Ubiquitinated. |
| Function | Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors. |
| Protein Name | G Protein-Coupled Receptor Kinase 3Beta-Adrenergic Receptor Kinase 2Beta-Ark-2 |
| Database Links | Reactome: R-HSA-418555Reactome: R-HSA-8856825 |
| Cellular Localisation | PostsynapsePresynapse |
| Alternative Antibody Names | Anti-G Protein-Coupled Receptor Kinase 3 antibodyAnti-Beta-Adrenergic Receptor Kinase 2 antibodyAnti-Beta-Ark-2 antibodyAnti-GRK3 antibodyAnti-ADRBK2 antibodyAnti-BARK2 antibody |
Information sourced from Uniprot.org