Anti-GPX3 antibody (Internal) (STJ71124)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-GPX3 (Internal) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Applications | Pep-ELISA/WB/IHC |
| Host | Goat |
| Reactivity | Human/Mouse/Rat/Dog/Pig |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:8000.WB: Approx 26kDa band observed in Mouse Heart lysates (calculated MW of 27.7kDa according to Mouse NP_001077398.1 [isoform1] and 25.4kDa according to Mouse NP_032187.2 [isoform 2] ). Recomm |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | GPX3 |
| Gene ID | 2878 |
| Uniprot ID | GPX3_HUMAN |
| Accession Number | NP_002075.2 |
| Immunogen Region | Internal |
| Immunogen Sequence | NQFGKQEPGENSE |
| Specificity | This antibody may cross-react with epididymis-specific GPX5 and olfactory epithelium-speciific GPX6 |
Additional Info
| Post Translational Modifications | The N-terminus is blocked. |
| Function | Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione. |
| Protein Name | Glutathione Peroxidase 3Gpx-3Gshpx-3Extracellular Glutathione PeroxidasePlasma Glutathione PeroxidaseGpx-PGshpx-P |
| Database Links | Reactome: R-HSA-3299685 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Glutathione Peroxidase 3 antibodyAnti-Gpx-3 antibodyAnti-Gshpx-3 antibodyAnti-Extracellular Glutathione Peroxidase antibodyAnti-Plasma Glutathione Peroxidase antibodyAnti-Gpx-P antibodyAnti-Gshpx-P antibodyAnti-GPX3 antibodyAnti-GPXP antibody |
Information sourced from Uniprot.org