Anti-GPX2 antibody (70-174) [S3822RM] (STJ11103822)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal Glutathione Peroxidase 2 (70-174) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S3822RM |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GPX2 |
| Gene ID | 2877 |
| Uniprot ID | GPX2_HUMAN |
| Immunogen Region | 70-174 |
| Immunogen Sequence | QFGHQENCQNEEILNSLKYV RPGGGYQPTFTLVQKCEVNG QNEHPVFAYLKDKLPYPYDD PFSLMTDPKLIIWSPVRRSD VAWNFEKFLIGPEGEPFRRY SRTFP |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 70-174 of human Glutathione Peroxidase 2 (NP_002074.2). |
Additional Info
| Tissue Specificity | Mostly in liver and gastrointestinal tract, not found in heart or kidney. |
| Function | Catalyzes the reduction of hydroperoxides in a glutathione-dependent manner thus regulating cellular redox homeostasis. Can reduce small soluble hydroperoxides such as H2O2, cumene hydroperoxide and tert-butyl hydroperoxide, as well as several fatty acid-derived hydroperoxides. Cannot reduce phosphatidycholine hydroperoxide. |
| Protein Name | Glutathione Peroxidase 2Gpx-2Gshpx-2Gastrointestinal Glutathione PeroxidaseGlutathione Peroxidase-GastrointestinalGpx-GiGshpx-GiGlutathione Peroxidase-Related Protein 2Gprp-2Phospholipid Hydroperoxide Glutathione Peroxidase Gpx2 |
| Database Links | Reactome: R-HSA-2142688Reactome: R-HSA-2142712Reactome: R-HSA-2142770Reactome: R-HSA-3299685Reactome: R-HSA-5628897 |
| Cellular Localisation | CytoplasmCytosol |
| Alternative Antibody Names | Anti-Glutathione Peroxidase 2 antibodyAnti-Gpx-2 antibodyAnti-Gshpx-2 antibodyAnti-Gastrointestinal Glutathione Peroxidase antibodyAnti-Glutathione Peroxidase-Gastrointestinal antibodyAnti-Gpx-Gi antibodyAnti-Gshpx-Gi antibodyAnti-Glutathione Peroxidase-Related Protein 2 antibodyAnti-Gprp-2 antibodyAnti-Phospholipid Hydroperoxide Glutathione Peroxidase Gpx2 antibodyAnti-GPX2 antibody |
Information sourced from Uniprot.org