Anti-GPT antibody (1-190) (STJ23848)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal GPT (1-190) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:200-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GPT |
| Gene ID | 2875 |
| Uniprot ID | ALAT1_HUMAN |
| Immunogen Region | 1-190 |
| Immunogen Sequence | MASSTGDRSQAVRHGLRAKV LTLDGMNPRVRRVEYAVRGP IVQRALELEQELRQGVKKPF TEVIRANIGDAQAMGQRPIT FLRQVLALCVNPDLLSSPNF PDDAKKRAERILQACGGHSL GAYSVSSGIQLIREDVARYI ERRDGGIPADPNNVFLSTGA SDAIVTVLKLLVAGEGHTRT GVLIPIPQYP |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human GPT (NP_005300.1). |
Additional Info
| Tissue Specificity | Liver, kidney, heart, and skeletal muscles. Expressed at moderate levels in the adipose tissue. |
| Function | Catalyzes the reversible transamination between alanine and 2-oxoglutarate to form pyruvate and glutamate. Participates in cellular nitrogen metabolism and also in liver gluconeogenesis starting with precursors transported from skeletal muscles. |
| Protein Name | Alanine Aminotransferase 1Alt1Glutamate Pyruvate Transaminase 1Gpt 1Glutamic--Alanine Transaminase 1Glutamic--Pyruvic Transaminase 1 |
| Database Links | Reactome: R-HSA-70268Reactome: R-HSA-8964540 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Alanine Aminotransferase 1 antibodyAnti-Alt1 antibodyAnti-Glutamate Pyruvate Transaminase 1 antibodyAnti-Gpt 1 antibodyAnti-Glutamic--Alanine Transaminase 1 antibodyAnti-Glutamic--Pyruvic Transaminase 1 antibodyAnti-GPT antibodyAnti-AAT1 antibodyAnti-GPT1 antibody |
Information sourced from Uniprot.org