| Host: |
Rabbit |
| Applications: |
IHC/IF/ELISA |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-G-protein-signaling modulator 1 (Internal) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
IHC 1:100-1:300ELISA 1:5000IF 1:50-200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
GPSM1 |
| Gene ID: |
26086 |
| Uniprot ID: |
GPSM1_HUMAN |
| Immunogen Region: |
Internal |
| Specificity: |
AGS3 Polyclonal Antibody detects endogenous levels of AGS3 protein. |
| Immunogen: |
Synthesized peptide derived from the Internal region of human AGS3. |
| Post Translational Modifications | Phosphorylation regulates interaction with G(i/o) alpha. |
| Function | Guanine nucleotide dissociation inhibitor (GDI) which functions as a receptor-independent activator of heterotrimeric G-protein signaling. Keeps G(i/o) alpha subunit in its GDP-bound form thus uncoupling heterotrimeric G-proteins signaling from G protein-coupled receptors. Controls spindle orientation and asymmetric cell fate of cerebral cortical progenitors. May also be involved in macroautophagy in intestinal cells. May play a role in drug addiction. |
| Protein Name | G-Protein-Signaling Modulator 1Activator Of G-Protein Signaling 3 |
| Database Links | Reactome: R-HSA-418594 |
| Cellular Localisation | CytoplasmCytosolEndoplasmic Reticulum MembranePeripheral Membrane ProteinCytoplasmic SideGolgi Apparatus MembraneCell Membrane |
| Alternative Antibody Names | Anti-G-Protein-Signaling Modulator 1 antibodyAnti-Activator Of G-Protein Signaling 3 antibodyAnti-GPSM1 antibodyAnti-AGS3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
