Anti-GPR88 antibody (STJ192659)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from part of the human protein
General Information
| Short Description | Rabbit polyclonal anti-Probable G-protein coupled receptor 88 for use in WB and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GPR88 |
| Gene ID | 54112 |
| Uniprot ID | GPR88_HUMAN |
| Immunogen | Synthesized peptide derived from part of the human protein |
| Specificity | GPR88 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | Orphan G protein-coupled receptor implicated in a large repertoire of behavioral responses that engage motor activities, spatial learning, and emotional processing. May play a role in the regulation of cognitive and motor function. Couples with the heterotrimeric G protein complex of the G(i) subfamily, consisting of GNAI1, GNB1 and GNG2, thereby acting through a G(i)-mediated pathway. Plays a role in the attenuation of D1 dopamine receptor (D1R)-mediated cAMP response in ciliated cells. In non-ciliated cells, involved in the inhibition of the beta-2 adrenergic receptor (B2AR) response. |
| Protein Name | G Protein-Coupled Receptor 88Striatum-Specific G-Protein Coupled Receptor |
| Database Links | |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinCell ProjectionCilium MembraneCytoplasmNucleusLocalized To Cilia In Ciliated CellsWhereas In Non-Ciliated CellsDistributed Throughout The Cell MembraneDuring Cortical LaminationSubcellular Location ShiftsOn The Day Of BirthFrom Expression At The Plasma Membrane And In The Cytoplasm To The Nuclei Of NeuronsThis Intranuclear Localization Remains Throughout Adulthood |
| Alternative Antibody Names | Anti-G Protein-Coupled Receptor 88 antibodyAnti-Striatum-Specific G-Protein Coupled Receptor antibodyAnti-GPR88 antibodyAnti-STRG antibody |
Information sourced from Uniprot.org