Anti-GPR68 nanobody [SAA1363] (STJN000277)

Anti-GPR68 nanobody [SAA1363] (STJN000277)

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STJN000277
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Covered by St John's Laboratory Guarantee

Host: Alpaca
Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Alpaca monoclonal nanobody anti-Ovarian Cancer G-Protein Coupled Receptor 1 is suitable for use in ELISA research applications.
Clonality : Monoclonal
Clone ID : SAA1363
Conjugation: Unconjugated
Isotype: VHH-8His-Cys-tag
Formulation: 0.01M PBS, pH 7.4.
Purification: Purified by Nickel column.
Concentration: 1 mg/mL
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at-20°C 12 months. Store at-80°C long term.
Gene Symbol: GPR68
Gene ID: 8111
Uniprot ID: OGR1_HUMAN
Function Proton-sensing receptor involved in pH homeostasis. May represents an osteoblastic pH sensor regulating cell-mediated responses to acidosis in bone. Mediates its action by association with G proteins that stimulates inositol phosphate (IP) production or Ca(2+) mobilization. The receptor is almost silent at pH 7.8 but fully activated at pH 6.8. Also functions as a metastasis suppressor gene in prostate cancer.
Protein Name Ovarian Cancer G-Protein Coupled Receptor 1
Ogr-1
G-Protein Coupled Receptor 68
Gpr12a
Sphingosylphosphorylcholine Receptor
Database Links Reactome: R-HSA-373076
Reactome: R-HSA-416476
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Nanobody Names Anti-Ovarian Cancer G-Protein Coupled Receptor 1 nanobody
Anti-Ogr-1 nanobody
Anti-G-Protein Coupled Receptor 68 nanobody
Anti-Gpr12a nanobody
Anti-Sphingosylphosphorylcholine Receptor nanobody
Anti-GPR68 nanobody
Anti-OGR1 nanobody

Information sourced from Uniprot.org

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