| Host: |
Rabbit |
| Applications: |
WB/IF/ELISA |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Ovarian cancer G-protein coupled receptor 1 (281-330 aa) is suitable for use in Western Blot, Immunofluorescence and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-1:2000IF 1:200-1:1000ELISA 1:5000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
GPR68 |
| Gene ID: |
8111 |
| Uniprot ID: |
OGR1_HUMAN |
| Immunogen Region: |
281-330 aa |
| Specificity: |
GPR68 Polyclonal Antibody detects endogenous levels of GPR68 protein. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from the human SPR1 at the amino acid range 281-330 |
| Function | Proton-sensing receptor involved in pH homeostasis. May represents an osteoblastic pH sensor regulating cell-mediated responses to acidosis in bone. Mediates its action by association with G proteins that stimulates inositol phosphate (IP) production or Ca(2+) mobilization. The receptor is almost silent at pH 7.8 but fully activated at pH 6.8. Also functions as a metastasis suppressor gene in prostate cancer. |
| Protein Name | Ovarian Cancer G-Protein Coupled Receptor 1Ogr-1G-Protein Coupled Receptor 68Gpr12aSphingosylphosphorylcholine Receptor |
| Database Links | Reactome: R-HSA-373076Reactome: R-HSA-416476 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Ovarian Cancer G-Protein Coupled Receptor 1 antibodyAnti-Ogr-1 antibodyAnti-G-Protein Coupled Receptor 68 antibodyAnti-Gpr12a antibodyAnti-Sphingosylphosphorylcholine Receptor antibodyAnti-GPR68 antibodyAnti-OGR1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
