Anti-GPR6 antibody (253-362) (STJ116938)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal GPR6 (253-362) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GPR6 |
| Gene ID | 2830 |
| Uniprot ID | GPR6_HUMAN |
| Immunogen Region | 253-362 |
| Immunogen Sequence | WRHAHQIALQQHCLAPPHLA ATRKGVGTLAVVLGTFGASW LPFAIYCVVGSHEDPAVYTY ATLLPATYNSMINPIIYAFR NQEIQRALWLLLCGCFQSKV PFRSRSPSEV |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 253-362 of human GPR6 (NP_005275.1). |
Additional Info
| Function | Orphan receptor with constitutive G(s) signaling activity that activate cyclic AMP. Promotes neurite outgrowth and blocks myelin inhibition in neurons. |
| Protein Name | G-Protein Coupled Receptor 6Sphingosine 1-Phosphate Receptor Gpr6 |
| Database Links | |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinDetected In The Intracellular CompartmentsIt Is Currently Unclear Whether This Is A Cell Surface Or Intracellular Receptor |
| Alternative Antibody Names | Anti-G-Protein Coupled Receptor 6 antibodyAnti-Sphingosine 1-Phosphate Receptor Gpr6 antibodyAnti-GPR6 antibody |
Information sourced from Uniprot.org