Anti-GPR17 antibody (C-Term) (STJ72062)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-GPR17 (C-Term) is suitable for use in ELISA, Western Blot and Immunofluorescence research applications. |
| Applications | Pep-ELISA/WB/IF |
| Host | Goat |
| Reactivity | Human/Mouse/Rat/Cow |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:4000.WB: Approx 40kDa band observed in Mouse Brain lysates (calculated MW of 37.8kDa according to Mouse NP_001020552.1 ). Recommended concentration: 2-3µg/ml. Primary incubation 1 hour at room t |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | GPR17 |
| Gene ID | 2840 |
| Uniprot ID | GPR17_HUMAN |
| Accession Number | NP_005282.1 |
| Immunogen Region | C-Term |
| Immunogen Sequence | EGKTNESSLSAKSE |
Additional Info
| Function | Dual specificity receptor for uracil nucleotides and cysteinyl leukotrienes (CysLTs). Signals through G(i) and inhibition of adenylyl cyclase. May mediate brain damage by nucleotides and CysLTs following ischemia. |
| Protein Name | Uracil Nucleotide/Cysteinyl Leukotriene ReceptorUdp/Cyslt ReceptorG-Protein Coupled Receptor 17P2y-Like ReceptorR12 |
| Database Links | Reactome: R-HSA-391906Reactome: R-HSA-416476Reactome: R-HSA-417957Reactome: R-HSA-418594 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Uracil Nucleotide/Cysteinyl Leukotriene Receptor antibodyAnti-Udp/Cyslt Receptor antibodyAnti-G-Protein Coupled Receptor 17 antibodyAnti-P2y-Like Receptor antibodyAnti-R12 antibodyAnti-GPR17 antibody |
Information sourced from Uniprot.org