Anti-GPIHBP1 antibody (1-51 aa) (STJ195681)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human HDBP1 at the amino acid range 1-51
General Information
| Short Description | Rabbit polyclonal anti-Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 (1-51 aa) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GPIHBP1 |
| Gene ID | 338328 |
| Uniprot ID | HDBP1_HUMAN |
| Immunogen | Synthesized peptide derived from the human HDBP1 at the amino acid range 1-51 |
| Immunogen Region | 1-51 aa |
| Specificity | This antibody detects endogenous levels of HDBP1 at Human/Mouse |
Additional Info
| Function | Mediates the transport of lipoprotein lipase LPL from the basolateral to the apical surface of endothelial cells in capillaries. Anchors LPL on the surface of endothelial cells in the lumen of blood capillaries. Protects LPL against loss of activity, and against ANGPTL4-mediated unfolding. Thereby, plays an important role in lipolytic processing of chylomicrons by LPL, triglyceride metabolism and lipid homeostasis. Binds chylomicrons and phospholipid particles that contain APOA5. Binds high-density lipoprotein (HDL) and plays a role in the uptake of lipids from HDL. |
| Protein Name | Glycosylphosphatidylinositol-Anchored High Density Lipoprotein-Binding Protein 1Gpi-Hbp1Gpi-Anchored Hdl-Binding Protein 1High Density Lipoprotein-Binding Protein 1 |
| Database Links | Reactome: R-HSA-163125Reactome: R-HSA-8963889Reactome: R-HSA-8963901Reactome: R-HSA-975634 |
| Cellular Localisation | Apical Cell MembraneLipid-AnchorGpi-AnchorBasolateral Cell MembraneCell Membrane |
| Alternative Antibody Names | Anti-Glycosylphosphatidylinositol-Anchored High Density Lipoprotein-Binding Protein 1 antibodyAnti-Gpi-Hbp1 antibodyAnti-Gpi-Anchored Hdl-Binding Protein 1 antibodyAnti-High Density Lipoprotein-Binding Protein 1 antibodyAnti-GPIHBP1 antibodyAnti-HBP1 antibody |
Information sourced from Uniprot.org