• Western blot analysis of lysates from DU145 cells, primary antibody was diluted at 1:1000, 4°C over night

Anti-GPIHBP1 antibody (1-51 aa) (STJ195681)

SKU:
STJ195681

Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 (1-51 aa) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: GPIHBP1
Gene ID: 338328
Uniprot ID: HDBP1_HUMAN
Immunogen Region: 1-51 aa
Specificity: This antibody detects endogenous levels of HDBP1 at Human/Mouse
Immunogen: Synthesized peptide derived from the human HDBP1 at the amino acid range 1-51
Function Mediates the transport of lipoprotein lipase LPL from the basolateral to the apical surface of endothelial cells in capillaries. Anchors LPL on the surface of endothelial cells in the lumen of blood capillaries. Protects LPL against loss of activity, and against ANGPTL4-mediated unfolding. Thereby, plays an important role in lipolytic processing of chylomicrons by LPL, triglyceride metabolism and lipid homeostasis. Binds chylomicrons and phospholipid particles that contain APOA5. Binds high-density lipoprotein (HDL) and plays a role in the uptake of lipids from HDL.
Protein Name Glycosylphosphatidylinositol-Anchored High Density Lipoprotein-Binding Protein 1
Gpi-Hbp1
Gpi-Anchored Hdl-Binding Protein 1
High Density Lipoprotein-Binding Protein 1
Database Links Reactome: R-HSA-163125
Reactome: R-HSA-8963889
Reactome: R-HSA-8963901
Reactome: R-HSA-975634
Cellular Localisation Apical Cell Membrane
Lipid-Anchor
Gpi-Anchor
Basolateral Cell Membrane
Cell Membrane
Alternative Antibody Names Anti-Glycosylphosphatidylinositol-Anchored High Density Lipoprotein-Binding Protein 1 antibody
Anti-Gpi-Hbp1 antibody
Anti-Gpi-Anchored Hdl-Binding Protein 1 antibody
Anti-High Density Lipoprotein-Binding Protein 1 antibody
Anti-GPIHBP1 antibody
Anti-HBP1 antibody

Information sourced from Uniprot.org

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