Anti-GPD1L antibody (1-351aa) [AT14E2] (STJA0041789)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1k
ImmunogenRecombinant human GPD1L (1-351aa) purified from E. coli
General Information
| Short Description | Mouse monoclonal anti-GPD1L (1-351aa) for use in ELISA, WB, ICC and IF in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ELISA/WB/ICC/IF |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | AT14E2 |
| Isotype | IgG1k |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | By protein-A affinity chromatography |
| Formulation | Liquid in phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GPD1L |
| Gene ID | 23171 |
| Uniprot ID | GPD1L_HUMAN |
| Accession Number | NP_055956 |
| Immunogen | Recombinant human GPD1L (1-351aa) purified from E. coli |
| Immunogen Region | 1-351aa |
Additional Info
| Tissue Specificity | Most highly expressed in heart tissue, with lower levels in the skeletal muscle, kidney, lung and other organs. |
| Function | Plays a role in regulating cardiac sodium current.decreased enzymatic activity with resulting increased levels of glycerol 3-phosphate activating the DPD1L-dependent SCN5A phosphorylation pathway, may ultimately lead to decreased sodium current.cardiac sodium current may also be reduced due to alterations of NAD(H) balance induced by DPD1L. |
| Protein Name | Glycerol-3-Phosphate Dehydrogenase 1-Like ProteinGpd1-L |
| Database Links | Reactome: R-HSA-1483166 |
| Cellular Localisation | CytoplasmLocalized To The Region Of The Plasma Membrane |
| Alternative Antibody Names | Anti-Glycerol-3-Phosphate Dehydrogenase 1-Like Protein antibodyAnti-Gpd1-L antibodyAnti-GPD1L antibodyAnti-KIAA0089 antibody |
Information sourced from Uniprot.org