Host: |
Rabbit |
Applications: |
WB/ELISA |
Reactivity: |
Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
Purification: |
Affinity purification |
Concentration: |
Lot specific |
Dilution Range: |
WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
GPAM |
Gene ID: |
57678 |
Uniprot ID: |
GPAT1_HUMAN |
Immunogen Region: |
630-730 |
Specificity: |
A synthetic peptide corresponding to a sequence within amino acids 630-730 of human GPAM (NP_065969.3). |
Immunogen Sequence: |
GTISLPCQTFYQVCHETVGK FIQYGILTVAEHDDQEDISP SLAEQQWDKKLPEPLSWRSD EEDEDSDFGEEQRDCYLKVS QSKEHQQFITFLQRLLGPLL E |
Function | Mitochondrial membrane protein that catalyzes the essential first step of biosynthesis of glycerolipids such as triglycerides, phosphatidic acids and lysophosphatidic acids. Esterifies acyl-group from acyl-coenzyme A (acyl-CoA) to the sn-1 position of glycerol-3-phosphate, to produce lysophosphatidic acid. Has a narrow hydrophobic binding cleft that selects for a linear acyl chain. Catalytic activity is higher for substrates with a 16-carbon acyl chain. |
Protein Name | Glycerol-3-Phosphate Acyltransferase 1 - MitochondrialGpat-1 |
Database Links | Reactome: R-HSA-1483166Reactome: R-HSA-2426168Reactome: R-HSA-75109Reactome: R-HSA-8931987Reactome: R-HSA-9018519 |
Cellular Localisation | Mitochondrion Outer MembranePeripheral Membrane ProteinAssociated With The Mitochondrion Outer Membrane Of Hepatic Cells Via A Patch Of Basic Residues |
Alternative Antibody Names | Anti-Glycerol-3-Phosphate Acyltransferase 1 - Mitochondrial antibodyAnti-Gpat-1 antibodyAnti-GPAM antibodyAnti-GPAT1 antibodyAnti-KIAA1560 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance