Anti-GOT2 antibody (30-430aa) [AT8B11] (STJA0041734)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG3k
ImmunogenRecombinant human GOT2 (30-430aa) purified from E.coli
General Information
| Short Description | Mouse monoclonal anti-GOT2 (30-430aa) for use in ELISA, WB, ICC, IF and FACS in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ELISA/WB/ICC/IF/FACS |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | AT8B11 |
| Isotype | IgG3k |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | By protein-A affinity chromatography |
| Formulation | Liquid in phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GOT2 |
| Gene ID | 2806 |
| Uniprot ID | AATM_HUMAN |
| Accession Number | NP_002071 |
| Immunogen | Recombinant human GOT2 (30-430aa) purified from E.coli |
| Immunogen Region | 30-430aa |
Additional Info
| Function | Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA). As a member of the malate-aspartate shuttle, it has a key role in the intracellular NAD(H) redox balance. Is important for metabolite exchange between mitochondria and cytosol, and for amino acid metabolism. Facilitates cellular uptake of long-chain free fatty acids. |
| Protein Name | Aspartate Aminotransferase - MitochondrialMaspatFatty Acid-Binding ProteinFabp-1Glutamate Oxaloacetate Transaminase 2Kynurenine Aminotransferase 4Kynurenine Aminotransferase IvKynurenine--Oxoglutarate Transaminase 4Kynurenine--Oxoglutarate Transaminase IvPlasma Membrane-Associated Fatty Acid-Binding ProteinFabppmTransaminase A |
| Database Links | Reactome: R-HSA-1614558Reactome: R-HSA-389661Reactome: R-HSA-8963693Reactome: R-HSA-8964539Reactome: R-HSA-9856872 |
| Cellular Localisation | Mitochondrion MatrixCell MembraneExposure To Alcohol Promotes Translocation To The Cell Membrane |
| Alternative Antibody Names | Anti-Aspartate Aminotransferase - Mitochondrial antibodyAnti-Maspat antibodyAnti-Fatty Acid-Binding Protein antibodyAnti-Fabp-1 antibodyAnti-Glutamate Oxaloacetate Transaminase 2 antibodyAnti-Kynurenine Aminotransferase 4 antibodyAnti-Kynurenine Aminotransferase Iv antibodyAnti-Kynurenine--Oxoglutarate Transaminase 4 antibodyAnti-Kynurenine--Oxoglutarate Transaminase Iv antibodyAnti-Plasma Membrane-Associated Fatty Acid-Binding Protein antibodyAnti-Fabppm antibodyAnti-Transaminase A antibodyAnti-GOT2 antibodyAnti-KYAT4 antibody |
Information sourced from Uniprot.org