Anti-GOT2 antibody (1-100) [S7MR] (STJ11102977)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal GOT2 (1-100) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S7MR |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GOT2 |
| Gene ID | 2806 |
| Uniprot ID | AATM_HUMAN |
| Immunogen Region | 1-100 |
| Immunogen Sequence | MALLHSGRVLPGIAAAFHPG LAAAASARASSWWTHVEMGP PDPILGVTEAFKRDTNSKKM NLGVGAYRDDNGKPYVLPSV RKAEAQIAAKNLDKEYLPIG |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human GOT2 (P00505). |
Additional Info
| Function | Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA). As a member of the malate-aspartate shuttle, it has a key role in the intracellular NAD(H) redox balance. Is important for metabolite exchange between mitochondria and cytosol, and for amino acid metabolism. Facilitates cellular uptake of long-chain free fatty acids. |
| Protein Name | Aspartate Aminotransferase - MitochondrialMaspatFatty Acid-Binding ProteinFabp-1Glutamate Oxaloacetate Transaminase 2Kynurenine Aminotransferase 4Kynurenine Aminotransferase IvKynurenine--Oxoglutarate Transaminase 4Kynurenine--Oxoglutarate Transaminase IvPlasma Membrane-Associated Fatty Acid-Binding ProteinFabppmTransaminase A |
| Database Links | Reactome: R-HSA-1614558Reactome: R-HSA-389661Reactome: R-HSA-8963693Reactome: R-HSA-8964539Reactome: R-HSA-9856872 |
| Cellular Localisation | Mitochondrion MatrixCell MembraneExposure To Alcohol Promotes Translocation To The Cell Membrane |
| Alternative Antibody Names | Anti-Aspartate Aminotransferase - Mitochondrial antibodyAnti-Maspat antibodyAnti-Fatty Acid-Binding Protein antibodyAnti-Fabp-1 antibodyAnti-Glutamate Oxaloacetate Transaminase 2 antibodyAnti-Kynurenine Aminotransferase 4 antibodyAnti-Kynurenine Aminotransferase Iv antibodyAnti-Kynurenine--Oxoglutarate Transaminase 4 antibodyAnti-Kynurenine--Oxoglutarate Transaminase Iv antibodyAnti-Plasma Membrane-Associated Fatty Acid-Binding Protein antibodyAnti-Fabppm antibodyAnti-Transaminase A antibodyAnti-GOT2 antibodyAnti-KYAT4 antibody |
Information sourced from Uniprot.org