Anti-GOLPH3 antibody (Internal) (STJ72120)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-GOLPH3 (Internal) is suitable for use in ELISA and Western Blot research applications. |
| Applications | Pep-ELISA/WB |
| Host | Goat |
| Reactivity | Human/Mouse/Dog/Cow |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:128000.WB: Approx 33kDa band observed in lysates of Human Platelets and Mouse Brain (calculated MW of 33.8kDa according to NP_071413.1). Recommended concentration: 0.1-0.3ยตg/ml. |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20ยฐC on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | GOLPH3 |
| Gene ID | 64083 |
| Uniprot ID | GOLP3_HUMAN |
| Accession Number | NP_071413.1 |
| Immunogen Region | Internal |
| Immunogen Sequence | DLATKRVRQLLDLD |
Additional Info
| Post Translational Modifications | Phosphorylated. |
| Function | Phosphatidylinositol-4-phosphate-binding protein that links Golgi membranes to the cytoskeleton and may participate in the tensile force required for vesicle budding from the Golgi. Thereby, may play a role in Golgi membrane trafficking and could indirectly give its flattened shape to the Golgi apparatus. May also bind to the coatomer to regulate Golgi membrane trafficking. May play a role in anterograde transport from the Golgi to the plasma membrane and regulate secretion. Has also been involved in the control of the localization of Golgi enzymes through interaction with their cytoplasmic part. May play an indirect role in cell migration. Has also been involved in the modulation of mTOR signaling. May also be involved in the regulation of mitochondrial lipids biosynthesis. |
| Protein Name | Golgi Phosphoprotein 3Coat Protein Gpp34Mitochondrial Dna Absence FactorMidas |
| Cellular Localisation | Golgi ApparatusGolgi Stack MembranePeripheral Membrane ProteinCytoplasmic SideTrans-Golgi Network MembraneMitochondrion Intermembrane SpaceCell MembraneEndosomePhosphatidylinositol 4-Phosphate-Binding And Oligomerization Participate In The Recruitment Onto Golgi Membranes |
| Alternative Antibody Names | Anti-Golgi Phosphoprotein 3 antibodyAnti-Coat Protein Gpp34 antibodyAnti-Mitochondrial Dna Absence Factor antibodyAnti-Midas antibodyAnti-GOLPH3 antibodyAnti-GPP34 antibody |
Information sourced from Uniprot.org