Anti-GOLGA1 antibody (1-300) (STJ116890)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal GOLGA1 (1-300) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GOLGA1 |
| Gene ID | 2800 |
| Uniprot ID | GOGA1_HUMAN |
| Immunogen Region | 1-300 |
| Immunogen Sequence | MFAKLKKKIAEETAVAQRPG GATRIPRSVSKESVASMGAD SGDDFASDGSSSREDLSSQL LRRNEQIRKLEARLSDYAEQ VRNLQKIKEKLEIALEKHQD SSMRKFQEQNETFQANRAKM AEGLALALARKDQEWSEKMD QLEKEKNILTAQLQEMKNQS MNLFQRRDEMDELEGFQQQE LSKIKHMLLKKEESLGKMEQ ELEARTRELSRTQEELMNSN QMSSDLSQKLEELQRHYST |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human GOLGA1 (NP_002068.1). |
Additional Info
| Post Translational Modifications | MARylated by PARP12.MARylation is required for basolateral export of E-Cadherin. |
| Function | Involved in vesicular trafficking at the Golgi apparatus level. Involved in endosome-to-Golgi trafficking. Mechanistically, captures transport vesicles arriving from endosomes via the protein TBC1D23. Recognized vesicles are then tethered to the trans-Golgi before subsequent SNARE engagement and vesicle fusion. Selectively regulates E-cadherin transport from the trans-Golgi network in tubulovesicular carriers. (Microbial infection) Plays an important role in poxvirus morphogenesis. Translocates into the viral factories where it may transport the membrane fragments and associated protein factors important for virus maturation to the sites of virion assembly. |
| Protein Name | Golgin Subfamily A Member 1Golgin-97 |
| Database Links | Reactome: R-HSA-6811440 |
| Cellular Localisation | Golgi Apparatus MembranePeripheral Membrane ProteinGolgi ApparatusTrans-Golgi Network MembraneCytoplasmic VesicleSecretory VesicleAcrosome |
| Alternative Antibody Names | Anti-Golgin Subfamily A Member 1 antibodyAnti-Golgin-97 antibodyAnti-GOLGA1 antibody |
Information sourced from Uniprot.org