Anti-GNRHR antibody (41-90 aa) (STJ93306)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human GNRHR at the amino acid range 41-90
General Information
| Short Description | Rabbit polyclonal anti-Gonadotropin-releasing hormone receptor (41-90 aa) for use in WB, IF and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IF 1:200-1:1000ELISA 1:5000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GNRHR |
| Gene ID | 2798 |
| Uniprot ID | GNRHR_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human GNRHR at the amino acid range 41-90 |
| Immunogen Region | 41-90 aa |
| Specificity | GnRH-R Polyclonal Antibody detects endogenous levels of GnRH-R protein. |
Additional Info
| Function | Receptor for gonadotropin releasing hormone (GnRH) that mediates the action of GnRH to stimulate the secretion of the gonadotropic hormones luteinizing hormone (LH) and follicle-stimulating hormone (FSH). This receptor mediates its action by association with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Isoform 2 may act as an inhibitor of GnRH-R signaling. |
| Protein Name | Gonadotropin-Releasing Hormone ReceptorGnrh ReceptorGnrh-R |
| Database Links | Reactome: R-HSA-375281Reactome: R-HSA-416476 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Gonadotropin-Releasing Hormone Receptor antibodyAnti-Gnrh Receptor antibodyAnti-Gnrh-R antibodyAnti-GNRHR antibodyAnti-GRHR antibody |
Information sourced from Uniprot.org