Anti-GNRH1 antibody (24-92) (STJ27592)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal GNRH1 (24-92) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GNRH1 |
| Gene ID | 2796 |
| Uniprot ID | GON1_HUMAN |
| Immunogen Region | 24-92 |
| Immunogen Sequence | QHWSYGLRPGGKRDAENLID SFQEIVKEVGQLAETQRFEC TTHQPRSPLRDLKGALESLI EEETGQKKI |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 24-92 of human GNRH1 (NP_001076580.1). |
Additional Info
| Post Translational Modifications | Gonadoliberin-1: The precursor is cleaved by ACE, which removes the Gly-Lys-Arg peptide at the C-terminus, leading to mature hormone. The mature form of Gonadoliberin-1 is also cleaved and degraded by ACE. |
| Function | Stimulates the secretion of gonadotropins.it stimulates the secretion of both luteinizing and follicle-stimulating hormones. |
| Protein Name | Progonadoliberin-1Progonadoliberin I Cleaved Into - Gonadoliberin-1Gonadoliberin IGonadorelinGonadotropin-Releasing Hormone IGnrh-ILuliberin ILuteinizing Hormone-Releasing Hormone ILh-Rh I - Gnrh-Associated Peptide 1Gnrh-Associated Peptide I |
| Database Links | Reactome: R-HSA-375281Reactome: R-HSA-416476 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Progonadoliberin-1 antibodyAnti-Progonadoliberin I Cleaved Into - Gonadoliberin-1 antibodyAnti-Gonadoliberin I antibodyAnti-Gonadorelin antibodyAnti-Gonadotropin-Releasing Hormone I antibodyAnti-Gnrh-I antibodyAnti-Luliberin I antibodyAnti-Luteinizing Hormone-Releasing Hormone I antibodyAnti-Lh-Rh I - Gnrh-Associated Peptide 1 antibodyAnti-Gnrh-Associated Peptide I antibodyAnti-GNRH1 antibodyAnti-GNRH antibodyAnti-GRH antibodyAnti-LHRH antibody |
Information sourced from Uniprot.org