| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-GNMT (1-295) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
GNMT |
| Gene ID: |
27232 |
| Uniprot ID: |
GNMT_HUMAN |
| Immunogen Region: |
1-295 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-295 of human GNMT (NP_061833.1). |
| Immunogen Sequence: |
MVDSVYRTRSLGVAAEGLPD QYADGEAARVWQLYIGDTRS RTAEYKAWLLGLLRQHGCQR VLDVACGTGVDSIMLVEEGF SVTSVDASDKMLKYALKERW NRRHEPAFDKWVIEEANWMT LDKDVPQSAEGGFDAVICLG NSFAHLPDCKGDQSEHRLAL KNIASMVRAGGLLVIDHRNY DHILSTGCAPPGKNIYYKSD LTKDVTTSVLIVNNKAHMVT LDYTVQVPGAGQDGSPGLS |
| Tissue Specificity | Expressed only in liver, pancreas, and prostate. |
| Function | Catalyzes the methylation of glycine by using S-adenosylmethionine (AdoMet) to form N-methylglycine (sarcosine) with the concomitant production of S-adenosylhomocysteine (AdoHcy), a reaction regulated by the binding of 5-methyltetrahydrofolate. Plays an important role in the regulation of methyl group metabolism by regulating the ratio between S-adenosyl-L-methionine and S-adenosyl-L-homocysteine. |
| Protein Name | Glycine N-Methyltransferase |
| Database Links | Reactome: R-HSA-2408508Reactome: R-HSA-389661 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Glycine N-Methyltransferase antibodyAnti-GNMT antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
