Anti-GNB2 antibody (1-90) [S4MR] (STJ11102514)

Name: Anti-GNB2 antibody (1-90) [S4MR] (STJ11102514)
SKU: STJ11102514
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityMonoclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ11102514

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Short Description	Rabbit monoclonal GNB2 (1-90) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/IHC-P/ELISA
Host	Rabbit
Reactivity	Human/Mouse/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Monoclonal
Clone ID	S4MR
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:500-1:1000 IHC-P:1:50-1:200 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	GNB2
Gene ID	2783
Uniprot ID	GBB2_HUMAN
Immunogen Region	1-90
Immunogen Sequence	MSELEQLRQEAEQLRNQIRD ARKACGDSTLTQITAGLDPV GRIQMRTRRTLRGHLAKIYA MHWGTDSRLLVSASQDGKLI IWDSYTTNKV
Specificity	Recombinant fusion protein containing a sequence corresponding to amino acids 1-90 of human GNB2 (P62879).

Tissue Specificity	Expressed in all cardiac subcompartments and in the brain, with highest levels in the atrioventricular node and brain.
Function	Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
Protein Name	Guanine Nucleotide-Binding Protein G(I/G(S/G(T Subunit Beta-2 G Protein Subunit Beta-2 Transducin Beta Chain 2
Database Links	Reactome: R-HSA-1296041 Reactome: R-HSA-163359 Reactome: R-HSA-202040 Reactome: R-HSA-381676 Reactome: R-HSA-392170 Reactome: R-HSA-392451 Reactome: R-HSA-392851 Reactome: R-HSA-400042 Reactome: R-HSA-4086398 Reactome: R-HSA-416476 Reactome: R-HSA-416482 Reactome: R-HSA-418217 Reactome: R-HSA-418555 Reactome: R-HSA-418592 Reactome: R-HSA-418594 Reactome: R-HSA-418597 Reactome: R-HSA-420092 Reactome: R-HSA-428930 Reactome: R-HSA-432040 Reactome: R-HSA-456926 Reactome: R-HSA-500657 Reactome: R-HSA-6814122 Reactome: R-HSA-8964315 Reactome: R-HSA-8964616 Reactome: R-HSA-9009391 Reactome: R-HSA-9634597 Reactome: R-HSA-9660821 Reactome: R-HSA-9856530 Reactome: R-HSA-997272
Cellular Localisation	Cytoplasm Perinuclear Region Cell Membrane
Alternative Antibody Names	Anti-Guanine Nucleotide-Binding Protein G(I/G(S/G(T Subunit Beta-2 antibody Anti-G Protein Subunit Beta-2 antibody Anti-Transducin Beta Chain 2 antibody Anti-GNB2 antibody

Information sourced from Uniprot.org