Anti-GNAT2 antibody (1-50 aa) (STJ93460)

SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human GNAT2 at the amino acid range 1-50
STJ93460
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General Information

Short DescriptionRabbit polyclonal anti-Guanine nucleotide-binding protein Gt subunit alpha-2 (1-50 aa) for use in WB, IHC, IF and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB/IHC/IF/ELISA
HostRabbit
ReactivityHuman/Mouse
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationUnconjugated
Concentration1 mg/mL
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution RangeWB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:10000
IF 1:50-200
FormulationLiquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage InstructionStore at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolGNAT2
Gene ID2780
Uniprot IDGNAT2_HUMAN
ImmunogenThe antiserum was produced against synthesized peptide derived from the human GNAT2 at the amino acid range 1-50
Immunogen Region1-50 aa
SpecificityG Alpha t2 Polyclonal Antibody detects endogenous levels of G Alpha t2 protein.

Additional Info

Function Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Transducin is an amplifier and one of the transducers of a visual impulse that performs the coupling between rhodopsin and cGMP-phosphodiesterase.
Protein Name Guanine Nucleotide-Binding Protein G(T Subunit Alpha-2
Transducin Alpha-2 Chain
Database Links Reactome: R-HSA-4086398
Reactome: R-HSA-418594
Cellular Localisation Cell Projection
Cilium
Photoreceptor Outer Segment
Photoreceptor Inner Segment
Localizes Mainly In The Outer Segment In The Dark-Adapted State
Whereas Is Translocated To The Inner Part Of The Photoreceptors In The Light-Adapted State
During Dark-Adapted Conditions
In The Presence Of Unc119 Mislocalizes From The Outer Segment To The Inner Part Of Rod Photoreceptors Which Leads To Decreased Photoreceptor Damage Caused By Light
Alternative Antibody Names Anti-Guanine Nucleotide-Binding Protein G(T Subunit Alpha-2 antibody
Anti-Transducin Alpha-2 Chain antibody
Anti-GNAT2 antibody
Anti-GNATC antibody

Information sourced from Uniprot.org

Citations

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