Anti-GMPPA antibody (184-234 aa) (STJ194545)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human GMPPA at the amino acid range 184-234
General Information
| Short Description | Rabbit polyclonal anti-Mannose-1-phosphate guanyltransferase alpha (184-234 aa) for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GMPPA |
| Gene ID | 29926 |
| Uniprot ID | GMPPA_HUMAN |
| Immunogen | Synthesized peptide derived from the human GMPPA at the amino acid range 184-234 |
| Immunogen Region | 184-234 aa |
| Specificity | This antibody detects endogenous levels of GMPPA at Human/Mouse/Rat |
Additional Info
| Function | Regulatory subunit of the GMPPA-GMPPB mannose-1-phosphate guanylyltransferase complex.reduces the catalytic activity of GMPPB when part of the complex. Mediates allosteric feedback inhibition of GMPPB catalytic activity upon binding GDP-alpha-D-mannose. Together with GMPPB regulates GDP-alpha-D-mannose levels. |
| Protein Name | Mannose-1-Phosphate Guanylyltransferase Regulatory Subunit AlphaGdp-Mannose Pyrophosphorylase AGmpp-AlphaGtp-Mannose-1-Phosphate Guanylyltransferase Alpha |
| Database Links | Reactome: R-HSA-446205 |
| Cellular Localisation | CytoplasmMyc-Tagged Gmppa Shows A Diffuse Cytoplasmic And Nuclear Pattern In Transfected Cos-7 Cells |
| Alternative Antibody Names | Anti-Mannose-1-Phosphate Guanylyltransferase Regulatory Subunit Alpha antibodyAnti-Gdp-Mannose Pyrophosphorylase A antibodyAnti-Gmpp-Alpha antibodyAnti-Gtp-Mannose-1-Phosphate Guanylyltransferase Alpha antibodyAnti-GMPPA antibody |
Information sourced from Uniprot.org