Anti-GlyT2 antibody [R08-1A3] (STJA0034380)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide of human Glyt2
General Information
| Short Description | Rabbit monoclonal anti-GlyT2 for use in WB in Human and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R08-1A3 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.3 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000 |
| Formulation | 50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | SLC6A5 |
| Gene ID | 9152 |
| Uniprot ID | SC6A5_HUMAN |
| Immunogen | A synthetic peptide of human Glyt2 |
Additional Info
| Tissue Specificity | Expressed in medulla, and to a lesser extent in spinal cord and cerebellum. |
| Post Translational Modifications | N-glycosylated. |
| Function | Sodium- and chloride-dependent glycine transporter. Terminates the action of glycine by its high affinity sodium-dependent reuptake into presynaptic terminals. May be responsible for the termination of neurotransmission at strychnine-sensitive glycinergic synapses. Isoform 2: Lacks sodium- and chloride-dependent glycine transporter activity. Isoform 3: Lacks sodium- and chloride-dependent glycine transporter activity. |
| Protein Name | Sodium- And Chloride-Dependent Glycine Transporter 2Glyt-2Glyt2Solute Carrier Family 6 Member 5 |
| Database Links | Reactome: R-HSA-442660Reactome: R-HSA-5619089 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Sodium- And Chloride-Dependent Glycine Transporter 2 antibodyAnti-Glyt-2 antibodyAnti-Glyt2 antibodyAnti-Solute Carrier Family 6 Member 5 antibodyAnti-SLC6A5 antibodyAnti-GLYT2 antibodyAnti-NET1 antibody |
Information sourced from Uniprot.org