Anti-Glycerol Kinase antibody [R05-9J4] (STJA0037401)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthesized peptide derived from human Glycerol kinase
General Information
| Short Description | Rabbit monoclonal anti-Glycerol Kinase for use in WB, IP and FC in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IP/FC |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R05-9J4 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000IP 1:50FC 1:50-1:100 |
| Formulation | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | GK |
| Gene ID | 2710 |
| Uniprot ID | GLPK_HUMAN |
| Immunogen | A synthesized peptide derived from human Glycerol kinase |
Additional Info
| Tissue Specificity | Isoform 2: Widely expressed in fetal and adult tissues. Isoform 3: Widely expressed in fetal and adult tissues. Isoform 4: The sole isoform expressed in adult liver and kidney. |
| Function | Kinase that plays a key role in glycerol metabolism, catalyzing its phosphorylation to produce sn-glycerol 3-phosphate. Sn-glycerol 3-phosphate is a crucial intermediate in various metabolic pathways, such as the synthesis of glycerolipids and triglycerides, glycogenesis, glycolysis and gluconeogenesis. |
| Protein Name | Glycerol KinaseGlycerokinaseAtp -Glycerol 3-Phosphotransferase |
| Database Links | Reactome: R-HSA-75109 |
| Cellular Localisation | Mitochondrion Outer MembraneSingle-Pass Membrane ProteinNucleusCytoplasmCytosolGlycerol Kinase Activity Is More Cytosolic In Some TissuesIt Probably Represents The Expression Of Isoforms Lacking A Transmembrane DomainIsoform 3: Mitochondrion Outer MembraneIn Sperm And Fetal TissuesThe Majority Of The Activity Is Associated With MitochondriaIsoform 4: CytoplasmIn Adult TissuesSuch As Liver The Glycerol Kinase Activity Is More CytosolicIt Probably Represents The Expression Of This Isoform Which Lacks A Transmembrane Domain |
| Alternative Antibody Names | Anti-Glycerol Kinase antibodyAnti-Glycerokinase antibodyAnti-Atp -Glycerol 3-Phosphotransferase antibodyAnti-GK antibody |
Information sourced from Uniprot.org