Anti-Glutathione Peroxidase 2 antibody [R02-1O9] (STJA0036998)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthesized peptide derived from human Glutathione Peroxidase 2
General Information
| Short Description | Rabbit monoclonal anti-Glutathione Peroxidase 2 for use in WB and IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R02-1O9 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Chromatography |
| Dilution Range | WB 1:500-1:1000IHC 1:50-1:100 |
| Formulation | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | GPX2 |
| Gene ID | 2877 |
| Uniprot ID | GPX2_HUMAN |
| Immunogen | A synthesized peptide derived from human Glutathione Peroxidase 2 |
Additional Info
| Tissue Specificity | Mostly in liver and gastrointestinal tract, not found in heart or kidney. |
| Function | Catalyzes the reduction of hydroperoxides in a glutathione-dependent manner thus regulating cellular redox homeostasis. Can reduce small soluble hydroperoxides such as H2O2, cumene hydroperoxide and tert-butyl hydroperoxide, as well as several fatty acid-derived hydroperoxides. Cannot reduce phosphatidycholine hydroperoxide. |
| Protein Name | Glutathione Peroxidase 2Gpx-2Gshpx-2Gastrointestinal Glutathione PeroxidaseGlutathione Peroxidase-GastrointestinalGpx-GiGshpx-GiGlutathione Peroxidase-Related Protein 2Gprp-2Phospholipid Hydroperoxide Glutathione Peroxidase Gpx2 |
| Database Links | Reactome: R-HSA-2142688Reactome: R-HSA-2142712Reactome: R-HSA-2142770Reactome: R-HSA-3299685Reactome: R-HSA-5628897 |
| Cellular Localisation | CytoplasmCytosol |
| Alternative Antibody Names | Anti-Glutathione Peroxidase 2 antibodyAnti-Gpx-2 antibodyAnti-Gshpx-2 antibodyAnti-Gastrointestinal Glutathione Peroxidase antibodyAnti-Glutathione Peroxidase-Gastrointestinal antibodyAnti-Gpx-Gi antibodyAnti-Gshpx-Gi antibodyAnti-Glutathione Peroxidase-Related Protein 2 antibodyAnti-Gprp-2 antibodyAnti-Phospholipid Hydroperoxide Glutathione Peroxidase Gpx2 antibodyAnti-GPX2 antibody |
Information sourced from Uniprot.org