Anti-Glutathione Peroxidase 1 antibody [R06-0H1] (STJA0035209)

SKU:
STJA0035209
$193.89 - $425.73
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Short Description :Rabbit monoclonal anti-Glutathione Peroxidase 1 for use in WB, ICC, IF and IP in Human and Rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB/ICC/IF/IP
Host:Rabbit
Reactivity:Human/Rat
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :R06-0H1
Isotype:IgG
Conjugation:Unconjugated
Concentration:0.3 mg/mL
Purification:Affinity Purified
Dilution Range:WB 1:500-1:1000
IF 1:50-1:200
IP 1:20
Formulation:50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Storage Instruction:Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.
Gene Symbol:GPX1
Gene ID:2876
Uniprot ID:GPX1_HUMAN
Immunogen:A synthetic peptide of human Glutathione Peroxidase 1
Tissue Specificity Expressed in platelets (at protein level).
Post Translational Modifications During periods of oxidative stress, Sec-49 may react with a superoxide radical, irreversibly lose hydroselenide and be converted to dehydroalanine.
Function Catalyzes the reduction of hydroperoxides in a glutathione-dependent manner thus regulating cellular redox homeostasis. Can reduce small soluble hydroperoxides such as H2O2, cumene hydroperoxide and tert-butyl hydroperoxide, as well as several fatty acid-derived hydroperoxides. In platelets catalyzes the reduction of 12-hydroperoxyeicosatetraenoic acid, the primary product of the arachidonate 12-lipoxygenase pathway.
Protein Name Glutathione Peroxidase 1
Gpx-1
Gshpx-1
Cellular Glutathione Peroxidase
Phospholipid-Hydroperoxide Glutathione Peroxidase Gpx1
Database Links Reactome: R-HSA-2142688
Reactome: R-HSA-2142712
Reactome: R-HSA-2142770
Reactome: R-HSA-3299685
Cellular Localisation Cytoplasm
Mitochondrion
Alternative Antibody Names Anti-Glutathione Peroxidase 1 antibody
Anti-Gpx-1 antibody
Anti-Gshpx-1 antibody
Anti-Cellular Glutathione Peroxidase antibody
Anti-Phospholipid-Hydroperoxide Glutathione Peroxidase Gpx1 antibody
Anti-GPX1 antibody

Information sourced from Uniprot.org