Anti-GLUT8/SLC2A8 antibody (C-Term) (STJ70961)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-GLUT8/SLC2A8 (C-Term) is suitable for use in ELISA research applications. |
| Applications | Pep-ELISA |
| Host | Goat |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:32000.WB: Preliminary experiments gave bands at approx 80kDa and 35kDa in Human Peripheral Blood Mononucleocyte lysates after 0.5µg/ml antibody staining. Please note that currently we cannot fin |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | SLC2A8 |
| Gene ID | 29988 |
| Uniprot ID | SL2A8_HUMAN |
| Accession Number | NP_055395.2 |
| Immunogen Region | C-Term |
| Immunogen Sequence | KGKTLEQITAH |
Additional Info
| Function | Insulin-regulated facilitative hexose transporter that mediates the transport of glucose and fructose. Facilitates hepatic influx of dietary trehalose, which in turn inhibits glucose and fructose influx triggering a starvation signal and hepatic autophagy through activation of AMPK and ULK1. Also able to mediate the transport of dehydroascorbate. |
| Protein Name | Solute Carrier Family 2 - Facilitated Glucose Transporter Member 8Glucose Transporter Type 8Glut-8Glucose Transporter Type X1 |
| Database Links | Reactome: R-HSA-189200Reactome: R-HSA-8856825Reactome: R-HSA-8856828 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinCytoplasmic Vesicle MembranePrincipally IntracellularMay Move Between Intracellular Vesicles And The Plasma MembraneThe Dileucine Internalization Motif Is Critical For Intracellular Sequestration |
| Alternative Antibody Names | Anti-Solute Carrier Family 2 - Facilitated Glucose Transporter Member 8 antibodyAnti-Glucose Transporter Type 8 antibodyAnti-Glut-8 antibodyAnti-Glucose Transporter Type X1 antibodyAnti-SLC2A8 antibodyAnti-GLUT8 antibodyAnti-GLUTX1 antibody |
Information sourced from Uniprot.org