• Immunohistochemistry of rat kidney with Anti-Glucose Transporter GLUT 4 primary antibody (STJ501214) at 1:100 dilution in Buffer. Section was treated with DAB and Haematoxylin stain. Magnification is at 40X.

Anti-GLUT4 antibody (450-509) (STJ501214)

SKU:
STJ501214-100

£481.50
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Host: Rabbit
Applications: CM/ELISA/ICC/IF/IHC/IP/WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-GLUT4 (450-509) is suitable for use in Confocal Microscopy, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Purification: Affinity Purified
Concentration: 0.5 µg/µl
Dilution Range: WB: 1:1, 000
DB: 1:4, 000
ELISA: 1:4, 000
IP: 1:200
IHC: 1:200
ICC: 1:200
IF: 1:200
CFM: 1:200
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: Slc2a4
Gene ID: 20528
Uniprot ID: GLUT4_MOUSE
Immunogen Region: 450-509
Immunogen: Synthetic peptide taken within amino acid region 450-509 on mouse Solute carrier family 2, facilitated glucose transporter member 4 protein.
Tissue Specificity Expressed in skeletal and cardiac muscles. Expressed in brown and white adipose tissues.
Post Translational Modifications Sumoylated. Palmitoylated. Palmitoylation by ZDHHC7 controls the insulin-dependent translocation of GLUT4 to the plasma membrane.
Function Insulin-regulated facilitative glucose transporter, which plays a key role in removal of glucose from circulation. Response to insulin is regulated by its intracellular localization: in the absence of insulin, it is efficiently retained intracellularly within storage compartments in muscle and fat cells. Upon insulin stimulation, translocates from these compartments to the cell surface where it transports glucose from the extracellular milieu into the cell.
Protein Name Solute Carrier Family 2 - Facilitated Glucose Transporter Member 4
Gt2
Glucose Transporter Type 4 - Insulin-Responsive
Glut-4
Database Links Reactome: R-MMU-189200
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Endomembrane System
Cytoplasm
Perinuclear Region
Localizes Primarily To The Perinuclear Region
Undergoing Continued Recycling To The Plasma Membrane Where It Is Rapidly Reinternalized
The Dileucine Internalization Motif Is Critical For Intracellular Sequestration
Insulin Stimulation Induces Translocation To The Cell Membrane
Alternative Antibody Names Anti-Solute Carrier Family 2 - Facilitated Glucose Transporter Member 4 antibody
Anti-Gt2 antibody
Anti-Glucose Transporter Type 4 - Insulin-Responsive antibody
Anti-Glut-4 antibody
Anti-Slc2a4 antibody
Anti-Glut4 antibody

Information sourced from Uniprot.org

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