Anti-GLUT2 antibody (Internal) (STJ73814)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-GLUT2 (Internal) is suitable for use in ELISA, Immunohistochemistry, Immunofluorescence and Flow Cytometry research applications. |
| Applications | Pep-ELISA/IHC/IF/FC |
| Host | Goat |
| Reactivity | Human/Mouse/Rat/Cow/Pig |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:8000.IHC: In paraffin embedded Human Liver shows strong staining of the endothelial lining cells. Recommended concentration: 2-6µg/ml.IF: Strong expression of the protein seen in the membra |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | SLC2A2 |
| Gene ID | 6514 |
| Uniprot ID | GTR2_HUMAN |
| Accession Number | NP_000331.1 |
| Immunogen Region | Internal |
| Immunogen Sequence | RKEREEASSEQKVS |
Additional Info
| Post Translational Modifications | N-glycosylated.required for stability and retention at the cell surface of pancreatic beta cells. |
| Function | Facilitative hexose transporter that mediates the transport of glucose, fructose and galactose. Likely mediates the bidirectional transfer of glucose across the plasma membrane of hepatocytes and is responsible for uptake of glucose by the beta cells.may comprise part of the glucose-sensing mechanism of the beta cell. May also participate with the Na(+)/glucose cotransporter in the transcellular transport of glucose in the small intestine and kidney. Also able to mediate the transport of dehydroascorbate. |
| Protein Name | Solute Carrier Family 2 - Facilitated Glucose Transporter Member 2Glucose Transporter Type 2 - LiverGlut-2 |
| Database Links | Reactome: R-HSA-189200Reactome: R-HSA-210745Reactome: R-HSA-422356Reactome: R-HSA-5619098Reactome: R-HSA-8981373 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Solute Carrier Family 2 - Facilitated Glucose Transporter Member 2 antibodyAnti-Glucose Transporter Type 2 - Liver antibodyAnti-Glut-2 antibodyAnti-SLC2A2 antibodyAnti-GLUT2 antibody |
Information sourced from Uniprot.org