![Anti-GLUT1 antibody [SM4989] (STJA0004989)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/124x110/products/180053/403326/STJA0004989_1__47451.1738950392.png?c=1 "Anti-GLUT1 antibody [SM4989] (STJA0004989)")
![Anti-GLUT1 antibody [SM4989] (STJA0004989)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/1280x1280/products/180053/403326/STJA0004989_1__47451.1738950392.png?c=1 "Anti-GLUT1 antibody [SM4989] (STJA0004989)")
Anti-GLUT1 antibody [SM4989] (STJA0004989)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
ImmunogenSynthesized peptide derived from human GLUT-1
General Information
| Short Description | Mouse monoclonal anti-GLUT1 for use in IHC and IF in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/IF |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SM4989 |
| Conjugation | Unconjugated |
| Purification | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
| Dilution Range | IHC/IF (H) 1:200-1:500 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Storage Instruction | Store at-20C for up to one year, and avoid repeated freeze-thaw cycles. |
Target Information
| Gene Symbol | SLC2A1 |
| Gene ID | 6513 |
| Uniprot ID | GTR1_HUMAN |
| Immunogen | Synthesized peptide derived from human GLUT-1 |
Additional Info
| Post Translational Modifications | Phosphorylation at Ser-226 by PKC promotes glucose uptake by increasing cell membrane localization. |
| Function | Facilitative glucose transporter, which is responsible for constitutive or basal glucose uptake. Has a very broad substrate specificity.can transport a wide range of aldoses including both pentoses and hexoses. Most important energy carrier of the brain: present at the blood-brain barrier and assures the energy-independent, facilitative transport of glucose into the brain. In association with BSG and NXNL1, promotes retinal cone survival by increasing glucose uptake into photoreceptors. Required for mesendoderm differentiation. |
| Protein Name | Solute Carrier Family 2 - Facilitated Glucose Transporter Member 1Glucose Transporter Type 1 - Erythrocyte/BrainGlut-1Hepg2 Glucose Transporter |
| Database Links | Reactome: R-HSA-189200Reactome: R-HSA-196836Reactome: R-HSA-422356Reactome: R-HSA-5619043Reactome: R-HSA-5653890 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinMelanosomePhotoreceptor Inner SegmentLocalizes Primarily At The Cell SurfaceIdentified By Mass Spectrometry In Melanosome Fractions From Stage I To Stage Iv |
| Alternative Antibody Names | Anti-Solute Carrier Family 2 - Facilitated Glucose Transporter Member 1 antibodyAnti-Glucose Transporter Type 1 - Erythrocyte/Brain antibodyAnti-Glut-1 antibodyAnti-Hepg2 Glucose Transporter antibodyAnti-SLC2A1 antibodyAnti-GLUT1 antibody |
Information sourced from Uniprot.org