Anti-Glucagon antibody [BS71] (STJ16101357)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1
General Information
| Short Description | Mouse monoclonal antibody anti-Glucagon is suitable for use in Immunohistochemistry research applications. |
| Applications | IHC-P |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | BS71 |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Dilution Range | IHC-P 1:100-1:400 |
| Formulation | TRIS with 0.03% sodium azide, pH7, 2 |
| Storage Instruction | Store at 2-8°C upon receipt. |
Target Information
Additional Info
| Background | Glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon. Glucagon is secreted in the alpha cells of the islets of Langerhans. GLP-1, GLP-2, oxyntomodulin and glicentin are secreted from enteroendocrine cells throughout the gastrointestinal tract. GLP1 and GLP2 are also secreted in selected neurons in the brain. |
Information sourced from Uniprot.org