Anti-GLRA1 antibody (N-Term) (STJA0003667)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthetic peptide corresponding to amino acid residues from the N-terminal region conjugated to KLH.
General Information
| Short Description | Rabbit polyclonal anti-Glycine Receptor (N-Term) for use in WB and IHC in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | This antibody was antigen affinity purified from pooled serum. |
| Dilution Range | WB 1:1000IHC 1:1000 |
| Formulation | Lyophilized |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | Glra1 |
| Gene ID | 25674 |
| Uniprot ID | GLRA1_RAT |
| Immunogen | Synthetic peptide corresponding to amino acid residues from the N-terminal region conjugated to KLH. |
| Immunogen Region | N-Term |
Additional Info
| Tissue Specificity | Detected in spinal cord (at protein level). Detected in spinal cord and brain stem. |
| Function | Subunit of heteromeric glycine-gated chloride channels. Plays an important role in the down-regulation of neuronal excitability. Contributes to the generation of inhibitory postsynaptic currents. Channel activity is potentiated by ethanol. Potentiation of channel activity by intoxicating levels of ethanol contribute to the sedative effects of ethanol. |
| Protein Name | Glycine Receptor Subunit Alpha-1Glycine Receptor 48 Kda SubunitGlycine Receptor Strychnine-Binding Subunit |
| Database Links | Reactome: R-RNO-112314 |
| Cellular Localisation | Postsynaptic Cell MembraneMulti-Pass Membrane ProteinSynapsePerikaryonCell ProjectionDendriteCell Membrane |
| Alternative Antibody Names | Anti-Glycine Receptor Subunit Alpha-1 antibodyAnti-Glycine Receptor 48 Kda Subunit antibodyAnti-Glycine Receptor Strychnine-Binding Subunit antibodyAnti-Glra1 antibodyAnti-Glyr antibody |
Information sourced from Uniprot.org