Anti-GLIPR1L1 antibody (STJA0009454)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human GLIPR1L1
General Information
| Short Description | Rabbit polyclonal anti-GLIPR1-like protein 1 for use in WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GLIPR1L1 |
| Gene ID | 256710 |
| Uniprot ID | GPRL1_HUMAN |
| Immunogen | Synthesized peptide derived from human GLIPR1L1 |
| Specificity | This antibody detects endogenous levels of GLIPR1L1 at Human |
Additional Info
| Post Translational Modifications | N-glycosylated. N-glycosylation decreases during the transit in the caput. |
| Function | Required for optimal fertilization at the stage of sperm-oocyte fusion, plays a role in optimizing acrosome function, the translocation of IZUMO1 during the acrosome reaction and the fertilization process. Component of epididymosomes, one type of membranous microvesicules which mediate the transfer of lipids and proteins to spermatozoa plasma membrane during epididymal maturation. Also component of the CD9-positive microvesicules found in the cauda region. |
| Protein Name | Glipr1-Like Protein 1 |
| Database Links | |
| Cellular Localisation | Cytoplasmic VesicleSecretory VesicleAcrosomeCell MembraneLipid-AnchorGpi-AnchorExtracellular SideMembrane RaftSecretedLocated In The Connecting Piece Of Elongated Spermatids And SpermAlso Located In The Apical Region Of The Sperm Head After Sperm CapacitationWeakly Attached To The Cell Membrane And Later Secreted Into The Extracellular SpaceLocated On Sperm Equatorial Segment And NeckAssociated With Epididymosomes From The Caput And Cauda Epididymis |
| Alternative Antibody Names | Anti-Glipr1-Like Protein 1 antibodyAnti-GLIPR1L1 antibodyAnti-UNQ2972 antibodyAnti-PRO7434 antibody |
Information sourced from Uniprot.org