Anti-GLE1 antibody (1-300) (STJ115173)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal GLE1 (1-300) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GLE1 |
| Gene ID | 2733 |
| Uniprot ID | GLE1_HUMAN |
| Immunogen Region | 1-300 |
| Immunogen Sequence | MPSEGRCWETLKALRSSDKG RLCYYRDWLLRREDVLEECM SLPKLSSYSGWVVEHVLPHM QENQPLSETSPSSTSASALD QPSFVPKSPDASSAFSPASP ATPNGTKGKDESQHTESMVL QSSRGIKVEGCVRMYELVHR MKGTEGLRLWQEEQERKVQA LSEMASEQLKRFDEWKELKQ HKEFQDLREVMEKSSREALG HQEKLKAEHRHRAKILNLKL REAEQQRVKQAEQERLRKE |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human GLE1 (NP_001003722.1). |
Additional Info
| Function | Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. May be involved in the terminal step of the mRNA transport through the nuclear pore complex (NPC). |
| Protein Name | Mrna Export Factor Gle1Hgle1Gle1 Rna Export MediatorGle1-Like ProteinNucleoporin Gle1 |
| Database Links | Reactome: R-HSA-159236 |
| Cellular Localisation | NucleusCytoplasmShuttles Between The Nucleus And The CytoplasmShuttling Is Essential For Its Mrna Export FunctionIsoform 1: CytoplasmNuclear Pore ComplexIn The NucleusIsoform 1 Localizes To The Nuclear Pore Complex And Nuclear Envelope |
| Alternative Antibody Names | Anti-Mrna Export Factor Gle1 antibodyAnti-Hgle1 antibodyAnti-Gle1 Rna Export Mediator antibodyAnti-Gle1-Like Protein antibodyAnti-Nucleoporin Gle1 antibodyAnti-GLE1 antibodyAnti-GLE1L antibody |
Information sourced from Uniprot.org