Anti-GLDC antibody (580-749 aa) [SRM5318] (STJ11107222)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal GLDC (580-749 aa) antibody for use in WB, IHC-P, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SRM5318 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:25000-1:150000IHC-P:1:4000-1:16000IF/ICC:1:2000-1:8000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.09% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
Target Information
| Gene Symbol | GLDC |
| Gene ID | 2731 |
| Uniprot ID | GCSP_HUMAN |
| Immunogen Region | 580-749 aa |
| Immunogen Sequence | HPFVPLDQAQGYQQLFRELE KDLCELTGYDQVCFQPNSGA QGEYAGLATIRAYLNQKGEG HRTVCLIPKSAHGTNPASAH MAGMKIQPVEVDKYGNIDAV HLKAMVDKHKENLAAIMITY PSTNGVFEENISDVCDLIHQ HGGQVYLDGANMNAQVGICR PGDFGSDVSH |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 580-749 of human GLDC (NP_000161.2). |
Additional Info
| Function | The glycine cleavage system catalyzes the degradation of glycine. The P protein (GLDC) binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor.CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein (GCSH). |
| Protein Name | Glycine DehydrogenaseDecarboxylating - MitochondrialGlycine Cleavage System P ProteinGlycine DecarboxylaseGlycine DehydrogenaseAminomethyl-Transferring |
| Database Links | Reactome: R-HSA-6783984 |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-Glycine Dehydrogenase antibodyAnti-Decarboxylating - Mitochondrial antibodyAnti-Glycine Cleavage System P Protein antibodyAnti-Glycine Decarboxylase antibodyAnti-Glycine Dehydrogenase antibodyAnti-Aminomethyl-Transferring antibodyAnti-GLDC antibodyAnti-GCSP antibody |
Information sourced from Uniprot.org