| Short Description : | Rabbit polyclonal anti-Glycerol kinase 2 (281-330 aa) for use in WB, IHC, IF and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IHC/IF/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:20000 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | GK2 |
| Gene ID: | 2712 |
| Uniprot ID: | GLPK2_HUMAN |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human GK2 at the amino acid range 281-330 |
| Immunogen Region: | 281-330 aa |
| Specificity: | GK2 Polyclonal Antibody detects endogenous levels of GK2 protein. |
| Function | Key enzyme in the regulation of glycerol uptake and metabolism. Essential for male fertility and sperm mitochondrial sheath formation. Required for proper arrangement of crescent-like mitochondria to form the mitochondrial sheath during spermatogenesis. Can induce mitochondrial clustering through interactions with PLD6 and up-regulation of phosphatidic acid synthesis in the mitochondria. |
| Protein Name | Glycerol Kinase 2Gk 2Glycerokinase 2Atp -Glycerol 3-Phosphotransferase 2Glycerol Kinase - Testis Specific 2 |
| Database Links | Reactome: R-HSA-75109 |
| Cellular Localisation | Mitochondrion Outer MembraneSingle-Pass Type Iv Membrane ProteinCytoplasmIn Sperm The Majority Of The Enzyme Is Bound To Mitochondria |
| Alternative Antibody Names | Anti-Glycerol Kinase 2 antibodyAnti-Gk 2 antibodyAnti-Glycerokinase 2 antibodyAnti-Atp -Glycerol 3-Phosphotransferase 2 antibodyAnti-Glycerol Kinase - Testis Specific 2 antibodyAnti-GK2 antibodyAnti-GKP2 antibodyAnti-GKTA antibody |
Information sourced from Uniprot.org
