Anti-GJA10 antibody (Cytoplasmic Domain) (STJ13100900)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide from 3d cytoplasmic domain of human Connexin-62 (CX62, Gap junction alpha-10 protein) conjugated to an immunogenic carrier protein was used as the antigen.
General Information
| Short Description | Rabbit polyclonal anti-GJA10 (Cytoplasmic Domain) for use in IHC and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | IgG purified |
| Dilution Range | IHC, WB. A dilution of 1:300 to 1:2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Formulation | Lyophilised |
| Storage Instruction | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
Target Information
| Gene Symbol | GJA10 |
| Gene ID | 84694 |
| Uniprot ID | CXA10_HUMAN |
| Immunogen | A synthetic peptide from 3d cytoplasmic domain of human Connexin-62 (CX62, Gap junction alpha-10 protein) conjugated to an immunogenic carrier protein was used as the antigen. |
| Immunogen Region | Cytoplasmic Domain |
| Specificity | Specific for Connexin-62. |
Additional Info
| Function | One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. Involved in tracer coupling between horizontal cells of the retina. May play a role in the regulation of horizontal cell patterning. |
| Protein Name | Gap Junction Alpha-10 ProteinConnexin-62Cx62 |
| Database Links | Reactome: R-HSA-112303Reactome: R-HSA-190861 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinCell JunctionGap Junction |
| Alternative Antibody Names | Anti-Gap Junction Alpha-10 Protein antibodyAnti-Connexin-62 antibodyAnti-Cx62 antibodyAnti-GJA10 antibodyAnti-CX62 antibody |
Information sourced from Uniprot.org