Anti-GITR antibody [ZN203] (STJA0033372)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2b
ImmunogenHuman recombinant protein fragment of human TNFRSF18 (NP_004186) produced in E.coli.
General Information
| Short Description | Mouse monoclonal anti-GITR for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-P |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | ZN203 |
| Isotype | IgG2b |
| Conjugation | Unconjugated |
| Concentration | 0.5-1.0 mg/mL |
| Purification | Affinity Chromatography |
| Dilution Range | IHC 1:50-1:100 |
| Formulation | PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | TNFRSF18 |
| Gene ID | 8784 |
| Uniprot ID | TNR18_HUMAN |
| Immunogen | Human recombinant protein fragment of human TNFRSF18 (NP_004186) produced in E.coli. |
Additional Info
| Tissue Specificity | Expressed in lymph node, peripheral blood leukocytes and weakly in spleen. |
| Function | Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway. |
| Protein Name | Tumor Necrosis Factor Receptor Superfamily Member 18Activation-Inducible Tnfr Family ReceptorGlucocorticoid-Induced Tnfr-Related ProteinCd Antigen Cd357 |
| Database Links | Reactome: R-HSA-5669034Reactome: R-HSA-8877330 |
| Cellular Localisation | Isoform 1: Cell MembraneSingle-Pass Type I Membrane ProteinIsoform 2: Secreted |
| Alternative Antibody Names | Anti-Tumor Necrosis Factor Receptor Superfamily Member 18 antibodyAnti-Activation-Inducible Tnfr Family Receptor antibodyAnti-Glucocorticoid-Induced Tnfr-Related Protein antibodyAnti-Cd Antigen Cd357 antibodyAnti-TNFRSF18 antibodyAnti-AITR antibodyAnti-GITR antibodyAnti-UNQ319 antibodyAnti-PRO364 antibody |
Information sourced from Uniprot.org