Anti-GITR antibody [DM78] (STJA0038110)

SKU:
STJA0038110-100
$596.85
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Short Description :Rabbit monoclonal anti-GITR for use in FC and ELISA in Human samples. Datasheet included with dilution recommendations, and related reagents.
Applications:FC/ELISA
Host:Rabbit
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :DM78
Isotype:IgG
Conjugation:Unconjugated
Purification:Affinity Chromatography
Dilution Range:FC 1:50-1:100
ELISA 1:10000
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Storage Instruction:Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.
Gene Symbol:TNFRSF18
Gene ID:8784
Uniprot ID:TNR18_HUMAN
Immunogen:Recombinant human GITR protein
Tissue Specificity Expressed in lymph node, peripheral blood leukocytes and weakly in spleen.
Function Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway.
Protein Name Tumor Necrosis Factor Receptor Superfamily Member 18
Activation-Inducible Tnfr Family Receptor
Glucocorticoid-Induced Tnfr-Related Protein
Cd Antigen Cd357
Database Links Reactome: R-HSA-5669034
Reactome: R-HSA-8877330
Cellular Localisation Isoform 1: Cell Membrane
Single-Pass Type I Membrane Protein
Isoform 2: Secreted
Alternative Antibody Names Anti-Tumor Necrosis Factor Receptor Superfamily Member 18 antibody
Anti-Activation-Inducible Tnfr Family Receptor antibody
Anti-Glucocorticoid-Induced Tnfr-Related Protein antibody
Anti-Cd Antigen Cd357 antibody
Anti-TNFRSF18 antibody
Anti-AITR antibody
Anti-GITR antibody
Anti-UNQ319 antibody
Anti-PRO364 antibody

Information sourced from Uniprot.org