Anti-GIRK-1 antibody (STJA0037546)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenPeptide
General Information
| Short Description | Rabbit monoclonal anti-GIRK-1 for use in WB and FC in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/FC |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Purified |
| Dilution Range | WB-1:1000-1:5000FC-1:100-1:500 |
| Formulation | Liquid in 50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | KCNJ3 |
| Gene ID | 3760 |
| Uniprot ID | KCNJ3_HUMAN |
| Immunogen | Peptide |
Additional Info
| Function | Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium.as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This potassium channel is controlled by G proteins. This receptor plays a crucial role in regulating the heartbeat. |
| Protein Name | G Protein-Activated Inward Rectifier Potassium Channel 1Girk-1Inward Rectifier K(+ Channel Kir3.1Potassium Channel - Inwardly Rectifying Subfamily J Member 3 |
| Database Links | Reactome: R-HSA-1296041Reactome: R-HSA-997272 |
| Cellular Localisation | MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-G Protein-Activated Inward Rectifier Potassium Channel 1 antibodyAnti-Girk-1 antibodyAnti-Inward Rectifier K(+ Channel Kir3.1 antibodyAnti-Potassium Channel - Inwardly Rectifying Subfamily J Member 3 antibodyAnti-KCNJ3 antibodyAnti-GIRK1 antibody |
Information sourced from Uniprot.org