Anti-GINS4 antibody (108-207) (STJ111324)

SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
STJ111324
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General Information

Short DescriptionRabbit polyclonal GINS4 (108-207) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB/ELISA
HostRabbit
ReactivityHuman/Mouse/Rat
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationUnconjugated
ConcentrationLot specific
PurificationAffinity purification
Dilution RangeWB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
FormulationPBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Storage InstructionStore at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolGINS4
Gene ID84296
Uniprot IDSLD5_HUMAN
Immunogen Region108-207
Immunogen SequenceLEKEKTRPEGEPSSLSPEEL AFAREFMANTESYLKNVALK HMPPNLQKVDLFRAVPKPDL DSYVFLRVRERQENILVEPD TDEQRDYVIDLEKGSQHLIR
SpecificityRecombinant fusion protein containing a sequence corresponding to amino acids 108-207 of human GINS4 (NP_115712.1).

Additional Info

Function Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex is a core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built.
Protein Name Dna Replication Complex Gins Protein Sld5
Gins Complex Subunit 4 Cleaved Into - Dna Replication Complex Gins Protein Sld5 - N-Terminally Processed
Database Links Reactome: R-HSA-176974
Cellular Localisation Nucleus
Chromosome
Cytoplasm
Associates With Chromatin
Alternative Antibody Names Anti-Dna Replication Complex Gins Protein Sld5 antibody
Anti-Gins Complex Subunit 4 Cleaved Into - Dna Replication Complex Gins Protein Sld5 - N-Terminally Processed antibody
Anti-GINS4 antibody
Anti-SLD5 antibody

Information sourced from Uniprot.org

Citations

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