Anti-GHRHR antibody (1-130) (STJ110719)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal GHRHR (1-130) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:100-1:500IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GHRHR |
| Gene ID | 2692 |
| Uniprot ID | GHRHR_HUMAN |
| Immunogen Region | 1-130 |
| Immunogen Sequence | MDRRMWGAHVFCVLSPLPTV LGHMHPECDFITQLREDESA CLQAAEEMPNTTLGCPATWD GLLCWPTAGSGEWVTLPCPD FFSHFSSESGAVKRDCTITG WSEPFPPYPVACPVPLELLA EEESYFSTVK |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-130 of human GHRHR (NP_000814.2). |
Additional Info
| Tissue Specificity | Pituitary gland. |
| Function | Receptor for GRF, coupled to G proteins which activate adenylyl cyclase. Stimulates somatotroph cell growth, growth hormone gene transcription and growth hormone secretion. |
| Protein Name | Growth Hormone-Releasing Hormone ReceptorGhrh ReceptorGrowth Hormone-Releasing Factor ReceptorGrf ReceptorGrfr |
| Database Links | Reactome: R-HSA-418555Reactome: R-HSA-420092 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Growth Hormone-Releasing Hormone Receptor antibodyAnti-Ghrh Receptor antibodyAnti-Growth Hormone-Releasing Factor Receptor antibodyAnti-Grf Receptor antibodyAnti-Grfr antibodyAnti-GHRHR antibody |
Information sourced from Uniprot.org